Table 4.
Most Commonly Reported Initiated Medications From Daily Journals Before Pregnancy During the 1-Year Study Follow-Up for Women and Men: LIFE Study, 2005 to 2009.a,b
| Medication Name | 1 to <3 Months (n = 501), n (%) | 3 to <6 Monthsc (n = 267), n (%) | 6 to <9 Monthsc (n = 133), n (%) | 9 to <12 Monthsc (n = 86), n (%) |
|---|---|---|---|---|
| Women | ||||
| Prenatal vitamin | 30 (6.0) | – | – | – |
| Amoxicillin | 13 (2.6) | – | – | – |
| Azithromycin | 13 (2.6) | 8 (3.0) | – | – |
| Hydrocodone/acetaminophen | 13 (2.6) | 5 (1.9) | – | – |
| Amoxicillin/potassium clavulanate | 9 (1.8) | – | – | – |
| Clomiphene citrate | 9 (1.8) | 12 (4.5) | 10 (7.5) | 7 (8.1) |
| Fluconazole | 8 (1.6) | – | – | – |
| Ciprofloxacin | 7 (1.4) | – | – | – |
| Diphenhydramine | 7 (1.4) | – | – | – |
| Metformin | 7 (1.4) | – | – | – |
| Naproxen | 7 (1.4) | – | – | – |
| Nitrofurantoin | 7 (1.4) | 5 (1.9) | – | – |
| Fexofenadine | 6 (1.2) | – | – | – |
| Fexofenadine/pseudoephedrine | 6 (1.2) | – | – | – |
| Ibuprofen | 6 (1.2) | – | – | – |
| Levofloxacin | 6 (1.2) | – | – | – |
| Progesterone | 6 (1.2) | 7 (2.6) | 6 (4.5) | – |
| Trimethoprim/sulfamethoxazole | 6 (1.2) | – | – | – |
| Valacyclovir | 6 (1.2) | – | – | – |
| Medroxyprogesterone | – | 8 (3.0) | 7 (5.3) | – |
| Men | ||||
| Azithromycin | 10 (2.0) | – | – | – |
| Amoxicillin | 7 (1.4) | – | – | – |
| Hydrocodone/acetaminophen | 6 (1.2) | – | – | – |
| Fexofenadine | 5 (1.0) | – | – | – |
| Naproxen | 5 (1.0) | – | – | – |
| Penicillin | 5 (1.0) | – | – | – |
| Prednisone | 5 (1.0) | – | – | – |
Abbreviation: LIFE, Longitudinal Study of Infertility and the Environment.
aCell counts of <5.
bMedications reported by ≥1% of the cohort.
cExcludes couples who were censored due to pregnancy or withdrawal from the study before the start of the interval.