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. 2017 Apr 26;25(1):120–130. doi: 10.1177/1933719117704908

Figure 3.

Figure 3.

Effect of melatonin on respiratory parameters in trophoblasts of obese women: mitochondrial respiratory parameters of the synctiotrophoblasts from obese women (n = 9), with and without melatonin (0.1-100 µmol/L) were measured in SeahorseXF24. Measurements in the presence of melatonin were expressed as a ratio normalized to the values in the untreated control, scatter plot with mean ± SEM. Basal respiration (A), ATP-coupled respiration (B), maximal respiration (C), and spare capacity (D). C, Obese maximal respiration melatonin versus control: 10 µmol/L (**P = .01) and 100 µmol/L (*P = .009). D, Obese spare capacity melatonin versus control: 10 µmol/L (**P = .02) and 100 µmol/L (*P = .003). ATP indicates adenosine triphosphate; SEM, standard error of the mean.