Table 5.
Hematologic and nonhematologic adverse events which ever occurred in 39 patients treated with FOLFIRINOX as a second-line treatment
| Adverse event | Any grade | Grade 3 or more | ||
|---|---|---|---|---|
| Number of patients | % | Number of patients | % | |
| Hematologic | ||||
| Neutropenia | 18 | 46.2 | 16 | 41.0 |
| Thrombocytopenia | 7 | 17.9 | 1 | 2.6 |
| Anemia | 23 | 59.0 | 3 | 7.7 |
| Nonhematologic | ||||
| Nausea | 23 | 59.0 | 4 | 10.3 |
| Vomiting | 3 | 7.7 | 1 | 2.6 |
| Diarrhea | 11 | 28.2 | 1 | 2.6 |
| Fatigue | 9 | 23.1 | 2 | 5.1 |
| Anorexia | 21 | 53.8 | 4 | 10.3 |
| Constipation | 6 | 15.4 | ||
| Mucositis | 12 | 30.8 | 3 | 7.7 |
| Neuropathy | 5 | 12.8 | 1 | 2.6 |
| Septic shock | 1a | 2.6 | ||
| Pneumonia/pleural effusion | 2 | 5.1 | ||
| Abdominal distension | 1 | 2.6 | ||
| Alkaline phosphatase increased | 1 | 2.6 | ||
| Hypokalemia | 1 | 2.6 | ||
| Glossopharyngeal neuralgia | 1 | 2.6 | ||
aGrade 5 (death)