Table 2.
Summary of acute adverse effects in 45 patients treated with bevacizumab in combination with neoadjuvant chemoradiotherapy
| Toxicity (NCI-CTC Version 3.0) | No. of patients | |||
|---|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
| Hematological | ||||
| Leukopenia | 11 | 8 | 3 | 1 |
| Neutropenia | 16 | 6 | 1 | 1 |
| Thrombocytopenia | 1 | 0 | 0 | 0 |
| Non-hematological | ||||
| Diarrhea | 10 | 2 | 2 | 0 |
| Nausea or vomiting | 17 | 2 | 0 | 0 |
| Hand-foot syndrome | 3 | 0 | 0 | 0 |
| Radiation dermatitis | 4 | 0 | 1 | 0 |
| Neuropathy | 15 | 0 | 0 | 0 |
| Proteinuria | 2 | 0 | 0 | 0 |