Table 3.
Suprathreshold clusters associated with CP and CU severity: Univariate and multivariate regressions.
| Peak Coordinates (MNI) |
||||||||
|---|---|---|---|---|---|---|---|---|
| Brain Region | R/L | Voxels | X | Y | Z | z-score | p-value | |
| Bivariate Associations | ||||||||
| Big Reward | ||||||||
| CP (- association) | Amygdala | L | 20 | −22 | −3 | −19 | 2.61 | 0.005 |
| Big Punishment | ||||||||
| CP (- association) | Amygdala | R | 46 | 34 | 3 | −22 | 4.22 | 0.000 |
| Amygdala | L | 40 | −28 | 0 | −22 | 3.88 | 0.000 | |
| Striatum | R/L | 279 | 3 | −3 | −12 | 3.99 | 0.000 | |
| ACC | R/L | 178 | 0 | 31 | −6 | 3.73 | 0.000 | |
| mPFC | L | 23 | −3 | 53 | −6 | 3.28 | 0.001 | |
| CU (- association) | Amygdala | L | 26 | −28 | 0 | −25 | 3.75 | 0.000 |
| Amygdala | R | 25 | 34 | 3 | −22 | 3.00 | 0.001 | |
| Caudate/Putamen | L | 16 | −19 | 19 | 9 | 2.99 | 0.001 | |
| Unique Associations | ||||||||
| Big Reward | ||||||||
| CP controlling for CU (- association) | Amygdala | L | 13 | −19 | −3 | 19 | 2.77 | 0.004 |
| CU controlling for CP (+ association) | Caudate | R | 13 | 19 | −12 | 25 | 3.45 | 0.000 |
| Big Punishment | ||||||||
| CP controlling for CU (- association) | Amygdala | R | 33 | 34 | 3 | −22 | 3.06 | 0.001 |
| Amygdala | L | 29 | −22 | −6 | −15 | 2.77 | 0.003 | |
Note. R = right; L = left; CP = conduct problems; CU = callous-unemotional traits; + = positive; − = negative; mPFC = medial prefrontal cortex.