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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Epilepsia. 2017 Dec 15;59(1):37–66. doi: 10.1111/epi.13965

Table 1. Clinical risk factors for developing epilepsy after TBI, CVA and infection.

Data are from Englander et al.321, Annegers et al.322, Graham et al.323, Annegers et al.324, and Haapaniemi et al.325

Risk Factor % Epilepsy Risk
PTE Early post-traumatic seizures 26
Glasgow coma scale (GCS) 3-8 17
Glasgow coma scale 9-12 24
Glasgow coma scale 13-15 8
Mid-line shift 1-5 mm 15-18
Mid-Line shift > 5 mm 26
Contusion, Cortical multiple 25
Contusion, Cortical single 8
Contusion, Subcortical single 16
Contusion, Subcortical multiple 33
Contusions, Frontal unilateral 20
bilateral 26
Contusion, Temporal unilateral 16
bilateral 31
Contusion, Parietal unilateral 19
bilateral 66
Subdural hematoma (SDH) 15
SDH requiring surgery 28-44
SDH + contusions 35
Surgery, single 14
Multiple 37
Fragment penetration, bone 0
metal 25
bone & metal 63
Depressed skull fracture 27
CVA Total Anterior Circulation 29
Early seizures (after ICH) 27
Intracranial haemorrhage (ICH) 18
Cortical location 19-25
Partial anterior circulation 13
Age < 65 years 16
GCS < 8 28
 9-12 25
 13-15 11
Barthel Index severe 13
  mild 8
Subarachnoid hemorrhage 22
Infection Bacterial meningitis, with early seizure 13
without early seizure 2
Viral encephalitis, with early seizure 22
without early seizure 10