Table 1. Clinical risk factors for developing epilepsy after TBI, CVA and infection.
Data are from Englander et al.321, Annegers et al.322, Graham et al.323, Annegers et al.324, and Haapaniemi et al.325
Risk Factor | % Epilepsy Risk | ||
---|---|---|---|
PTE | Early post-traumatic seizures | 26 | |
Glasgow coma scale (GCS) | 3-8 | 17 | |
Glasgow coma scale | 9-12 | 24 | |
Glasgow coma scale | 13-15 | 8 | |
Mid-line shift 1-5 mm | 15-18 | ||
Mid-Line shift > 5 mm | 26 | ||
Contusion, Cortical | multiple | 25 | |
Contusion, Cortical | single | 8 | |
Contusion, Subcortical | single | 16 | |
Contusion, Subcortical | multiple | 33 | |
Contusions, Frontal | unilateral | 20 | |
bilateral | 26 | ||
Contusion, Temporal | unilateral | 16 | |
bilateral | 31 | ||
Contusion, Parietal | unilateral | 19 | |
bilateral | 66 | ||
Subdural hematoma (SDH) | 15 | ||
SDH requiring surgery | 28-44 | ||
SDH + contusions | 35 | ||
Surgery, single | 14 | ||
Multiple | 37 | ||
Fragment penetration, | bone | 0 | |
metal | 25 | ||
bone & metal | 63 | ||
Depressed skull fracture | 27 | ||
CVA | Total Anterior Circulation | 29 | |
Early seizures (after ICH) | 27 | ||
Intracranial haemorrhage (ICH) | 18 | ||
Cortical location | 19-25 | ||
Partial anterior circulation | 13 | ||
Age < 65 years | 16 | ||
GCS < 8 | 28 | ||
9-12 | 25 | ||
13-15 | 11 | ||
Barthel Index severe | 13 | ||
mild | 8 | ||
Subarachnoid hemorrhage | 22 | ||
Infection | Bacterial meningitis, | with early seizure | 13 |
without early seizure | 2 | ||
Viral encephalitis, | with early seizure | 22 | |
without early seizure | 10 |