Table 1. Patients’ demographics and tumor’s characteristics.
| Frequency | % | |
|---|---|---|
| Age (range) | 65 (18–88) | |
| <70 | 260 | 65,5 |
| > = 70 | 137 | 34,5 |
| Gender | ||
| Male | 246 | 62,0 |
| Female | 151 | 38,0 |
| Stage | ||
| IIA-IIIC | 202 | 50,9 |
| IV | 195 | 49,1 |
| Location | ||
| Colon/Sigmoid | 279 | 70,3 |
| Rectum | 118 | 29,7 |
| PS (ECOG) | ||
| 0–1 | 372 | 93,7 |
| > = 2 | 25 | 6,3 |
| Radiotherapy | ||
| Yes | 80 | 20,4 |
| No | 313 | 79,6 |
| Adjuvant Treatment | ||
| Yes | 230 | 58,7 |
| No | 162 | 41,4 |
| First Line Treatment | ||
| Yes | 223 | 56,2 |
| No | 174 | 46,8 |
| Grade | ||
| High | 205 | 47,4 |
| Low | 228 | 52.6 |
| TLR2 196-to -174 del | ||
| ins/del | 93 | 23,4 |
| del/del | 304 | 76,6 |
| TLR4 Asp299Gly (A/G) | ||
| AA | 11 | 2,8 |
| AG | 106 | 26,7 |
| GG | 280 | 70,5 |
| TLR4 Thr399Ile (T/C) | ||
| CC | 11 | 2,8 |
| CT | 106 | 26,7 |
| TT | 280 | 70,5 |
| TLR9 T1237C | ||
| TC | 153 | 38,5 |
| CC | 244 | 61,5 |
| TLR9 T1486C | ||
| TC | 153 | 38,5 |
| CC | 244 | 61,5 |
| KRAS | ||
| Mutant | 104 | 42,4 |
| Wt | 141 | 57,6 |
| ND | 152 |