Table 1.

Means of point estimates and actual coverage of interval estimates for the parameters of model (Equation (16)) according to four different experimental setups. The results are based on 500 simulation runs. The observations are generated according to $Y_j={\mathrm{\xi }}_0\exp \left({\mathrm{\theta }}_0{t}_j\right)+{\mathrm{ϵ}}_j$, where t _j∈{0(0.5)10} (n=21), or t _j∈{0(0.2)10} (n=51 ) and ϵ_j∼N(0,0.05²),j=1…,n. The point estimates are given by Equation 6; the interval estimates are defined in Equation 15

				One‐step		NLS
Setup				Mean	Coverage	Mean	Coverage
n = 21	A	ξ0	0.500	0.501	0.942	0.501	0.942
		θ0	−1.000	−1.002	0.946	−1.002	0.946
	B	ξ0	0.500	0.500	0.928	0.500	0.928
		θ0	1.000	1.000	0.938	1.000	0.938
	C	ξ0	1.000	0.999	0.932	0.999	0.932
		θ0	−1.000	−0.997	0.940	−0.997	0.940
	D	ξ0	1.000	1.000	0.944	1.000	0.944
		θ0	1.000	1.000	0.948	1.000	0.948
n = 51	A	ξ0	0.500	0.500	0.944	0.500	0.944
		θ0	−1.000	−0.998	0.944	−0.998	0.944
	B	ξ0	0.500	0.500	0.946	0.500	0.946
		θ0	1.000	0.999	0.958	0.999	0.958
	C	ξ0	1.000	0.999	0.932	0.999	0.932
		θ0	−1.000	−0.999	0.938	−1.000	0.938
	D	ξ0	1.000	1.000	0.948	1.000	0.948
		θ0	1.000	1.001	0.952	1.001	0.952

Note: NLS, non‐linear least squares.