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. 2018 Jun 8;13(6):e0198859. doi: 10.1371/journal.pone.0198859

Table 2. Between group differences across time.

Means and standard deviations of PP-cases [within-group differences are in square brackets].

Wait-list
(n = 39)
Deprexis
(n = 23)
Between-group difference pre-post; ANCOVAs with baseline scores as covariates
Pre
M (SD)
Post
M (SD)
Mean difference (95% CI) Pre
M (SD)
Post
M (SD)
Mean difference (95% CI) Per Protocol (PP) Intention to treat (ITT)*
Primary outcome
PHQ-9 10.26 (5.11) 8.26 (5.14) [*] 2.00 (.372–3.628) 9.39 (4.46) 5.74 (4.52) [***] 3.65 (1.742–5.562) F (1;59) = 3.40,
p = .070, ηp2 = .054
F(1;137) = 19.64,
p < .001, ηp2 = .125; [p = .030]
Secondary outcomes
SOGS 9.11 (2.98) 6.53 (4.08) [****] 3.09 (1.758–4.416) 8.43 (2.33) 5.35 (3.77) [****] 3.09 (1.758–4.416) F (1;58) = .55,
p = .462, ηp2 = .009
F(1;137) = 8.26,
p = .005, ηp2 = .057; [p = .118]
PG-YBOCS
total
16.13 (7.36) 13.51 (8.83) [*] 5.30 (2.052–8.557) 16.52 (6.03) 11.22 (7.67) [***] 5.30 (2.051–8.557) F (1;59) = 1.76,
p = .190, ηp2 = .029
F(1;137) = 4.01,
p = .047, ηp2 = .028; [p = .295]
PG-YBOCS
behaviour
7.56 (4.19) 6.33 (4.74) 1.23 (-.187–2.649) 8.26 (3.31) 5.30 (4.25) [**] 2.95 (.977–4.936) F (1;59) = 1.68,
p = .200, ηp2 = .028
F(1;137) = 3.21,
p = .076, ηp2 = .023; [p = .361]
PG-YBOCS
thoughts
8.56 (3.55) 7.18 (4.24) [*] 1.38 (.184–2.585) 8.97 (3.59) 5.91 (3.86) [**] 2.35 (.453–4.069) F (1;59) = 1.34,
p = .252, ηp2 = .022
F(1;137) = 3.99,
p = .048, ηp2 = .028; [p = .489]
GAD-7 7.51 (4.64) 7.23 (4.90) .28 (-1.205–1.769) 7.91 (5.01) 5.65 (4.20) [*] 2.26 (.453–4.069) F (1;59) = 3.06,
p = .085, ηp2 = .049
F(1;137) = 13.10,
p < .001, ηp2 = .087; [p = .053]

We present pairwise data of PP-analyses. For this reason pre-scores may deviate from those reported in Table 1.* ITT analyses were computed with EM as method for missing values.

[*] = p ≤ .05

[**] = p ≤ .01

[***] = p ≤ .005

[****] = p ≤ .001