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(A) Parameter distributions from ODE model (1)–(4) for all 8 kinetic parameters obtained via MCMC. Red vertical lines indicate the parameter values from experiments or maximum likelihood estimates [37]. Markov chain length was 106 steps. (B) Model simulation and polynomial outputs using the mean parameter set from the 8-parameter MCMC compared with the time-course (top) and dose-response (bottom) data.
