Table 2.
Study | Sample | Dosing | Outcomes |
---|---|---|---|
Mousavi et al18 (2015) | N = 32 treatment- seeking adults with methamphetamine dependence (83% male, 100% recruited from Iran) | 1,200 mg/d vs placebo (crossover design) for 4 weeks each | Reduction in methamphetamine cravings during treatment (but not after crossover) using the Cocaine Craving Questionnaire brief (CCQ- brief) |
Grant et al19 (2010) | N = 31 non- treatment seeking adults with methamphetamine dependence (71% male) | 2,400 mg/d NAC plus 200 mg/d naltrexone vs placebo for 8 weeks | No reduction in craving as measured by the Penn Craving Scale or frequency of use (urine drug screen) |
NAC: N-acetylcysteine