Table 1.
Mutual exclusivity of HLA class I-related genes Log odds ratio shows how strongly presence or absence of alterations in gene A are related with presence or absence of alterations in gene B. Log odds ratio of more than 0 corresponds association towards co-occurrence, equals to or less than 0 corresponds mutual exclusivity; p < 0,05 is significant association.
geneA | geneB | p-Value | Log Odds Ratio | Association |
---|---|---|---|---|
B2M | HLA-B | 0.005 | −2.359 | Tendency towards mutual exclusivity (Significant) |
HLA-A | HLA-B | <0,001 | 2.876 | Tendency towards co-occurance (Significant) |
HLA-A | HLA-C | <0,001 | >3 | Tendency towards co-occurance (Significant) |
HLA-B | HLA-C | 0.002 | 2.457 | Tendency towards co-occurance (Significant) |