Table 2.
Characteristics of 5 patients with increased PD-L1 expression after pre-operative radiation therapy.
| Gender | Age | Location | T stage | Grade | Histologic Subtype | Time Between Pre-Op RT & Sx (days) | Total Dose | % PDL1 staining at biopsy | % PDL1 staining at surgery/after RT |
|---|---|---|---|---|---|---|---|---|---|
| Male | 36 | Lower Limb | T2b | 3 | Epitheliod | 26 | 50 Gy/ 25 fx | 0 | > 1 |
| Male | 41 | Lower Limb | T2b | 3 | UPS | 27 | 50 Gy/ 25 fx | 0 | > 1 |
| Female | 60 | Lower Limb | T2b | 3 | UPS | 35 | 50 Gy/ 25 fx | 0 | > 1 |
| Male | 56 | Lower Limb | T2b | 3 | UPS | 17 | 50 Gy/ 25 fx | 0 | > 1 |
| Female | 70 | Lower Limb | T2b | 3 | UPS | 42 | 50 Gy/ 25 fx | 0 | > 1 |
Gy/fx = Gray/fraction; RT = radiation therapy; Sx = surgery; UPS = undifferentiated pleomorphic sarcoma.