Table 4. The univariate and multivariate regression analysis of the inflammatory factors with inflammatory responses after surgery.
| Dependent variable | Univariate analysis
(spearman correlation) |
Multivariate analysis
(LASSO and multivariate linear regression) |
|||||
|---|---|---|---|---|---|---|---|
| predictor | ρ | p (2-tailed) | Standardized coefficient (β) | p | Adjusted R Square | Significance of Regression in ANOVA | |
| EPCO |
IL-1RA |
−0.402 |
0.013 |
−0.382 |
0.015* |
0.161 |
0.025 |
| (one month after surgery, n=33) |
PDGF-AA |
0.497 |
0.03 |
0.415 |
0.044* |
|
|
| EPCO |
IL-1RA |
−0.413 |
0.029 |
−0.336 |
0.044* |
0.366 |
0.011 |
| (three months after surgery, n=30) |
IL-3 |
−0.524 |
0.006 |
−0.413 |
0.682 |
|
|
| |
TNFβ |
−0.402 |
0.046 |
−0.215 |
0.418 |
|
|
| |
PDGF-AA |
0.647 |
0.009 |
0.564 |
0.006* |
|
|
| EPCO |
MDC |
0.326 |
0.036 |
0.129 |
0.036* |
0.147 |
0.036 |
| (one year after surgery, n=22) | IL-7 | 0.402 | 0.005 | out# | / | ||
*P value <0.05 indicating statistical significance. # The inflammatory factor was excluded after filtered by LASSO model and was not further analyzed by multivariate linear regression.