Table 3.

Univariate and multivariate logistic regression analysis to identify determinants of significant MR (including three groups)

	Binary logistic regression for MR (Presence or absence of significant MR)
	Univariate			Multivariate
	OR	95% CI	P-value	OR	95% CI	P-value
Age	1.04	0.983–1.120	0.149
Sex	1.606	0.607–4.245	0.340
BSA	0.347	0.018–6.707	0.483
ESV index	1.022	0.583–1.022	0.583
EDV index	1.010	0.967–1.054	0.664
EF	0.968	0.897–1.045	0.405
LA volume index	1.098	1.053–1.146	<0.001
Annular area index	11.127	3.569–34.689	<0.001	5.529	1.517–20.161	0.010
Annular height	0.754	0.465–1.223	0.252
Fractional area change of the MA	0.840	0.770–0.916	<0.001
Anterior-posterior (AP) diameter index	2.022	1.464–2.794	<0.001
Intercommissural (IC) diameter index	1.789	1.333–2.400	<0.001
Non-planarity angle	1.171	1.076–1.275	<0.001
Circularity index of annulus*	3.450	1.644–7.238	0.001
Total annulus perimeter index	1.162	1.075–1.255	<0.001
Posterior to anterior perimeter ratio*	1.888	1.353–2.643	<0.001	2.371	1.025–5.485	0.044
Q2/Q3 ratio	1.307	0.038–44.990	0.882
Total MLA index	2.997	1.781–5.043	<0.001
Closure area index	7.308	2.949–18.112	<0.001
Total MLA to closure area ratio*	0.139	0.052–0.371	<0.001	0.185	0.053–0.642	0.008
Total MLA to AA ratio*	0.388	0.232–0.648	0.002
Tenting volume	8.136	2.768–23.913	<0.001
Anterior tenting angle	1.028	0.935–1.129	0.573
Posterior tenting angle	1.389	1.192–1.619	<0.001
X-coordinate of maximal tenting point	1.071	0.921–1.245	0.375
Y-coordinate of maximal tenting point	0.607	0.462–0.797	<0.001

OR, odds ratio; BSA, body surface area; ESV, end-systolic volume; EDV, end-diastolic volume; EF, ejection fraction; MLA, mitral leaflet area; MT, medial trigone; MP, medial papillary muscle; LT, lateral papillary muscle.

^*OR is for 10 unit increases in the independent variable.