Table 4.

Selected genes with suggestive p-values (<0.05) from multiple analyses

Gene	Chr	Position	Band	Sun-exposed Skin			Non-Sun-exposed Skin			SKAT
				z-score	p-value	N Variants/Model N†	z-score	p-value	N Variants/Model N†	p-value	N‡
SLPI	20	43881680–43881682	20q13.12	2.96	0.003	1/47	−2.06	0.039	3/77	0.004	1
ZNF337	20	25655765–25666737	20p11.1	−2.65	0.008	1/82	−2.65	0.008	1/28	0.032	4
ARFIP1	4	153791955–153802203	4q31.3	−2.21	0.027	1/15	−2.21	0.027	1/14	0.027	1
TMEM8B	9	35829222–35854844	9p13.3	−2.53	0.011	1/15	NA	NA	NA	0.004	5
TOR3A	1	179051112–179065129	1q25.2	−2.25	0.025	1/20	NA	NA	NA	0.043	2
MLXIPL	7	73010191–73020440	7q11.23	−2.62	0.009	3/16	−2.76	0.006	5/48	0.679	6
NAAA	4	76836110–76862005	4q21.1	2.73	0.006	4/46	2.63	0.009	3/31	0.263	8
ALDH16A1	19	49956613–49973578	19q13.33	−2.70	0.007	3/21	−2.30	0.022	2/58	0.423	14
CDRT4	17	15341161–15341332	17p12	2.56	0.010	2/23	2.67	0.008	1/31	0.234	13

Boldface represents p-values < 0.05.

^†Number of SNPs included in the prediction model for that gene available in the summary statistics/Number of SNPs used to construct the prediction model for the gene in the tissue of interest using the GTEx data.

^‡Number of SNPs with frequency <0.05 in the gene of interest and included in the analysis. NA = gene was not available in this analysis