Skip to main content
. Author manuscript; available in PMC: 2018 Sep 15.
Published in final edited form as: Oncogene. 2018 Mar 15;37(23):3151–3165. doi: 10.1038/s41388-018-0178-3

Figure 7. miR-21−/− macrophages exerted stronger anti-tumor effects than their WT counterparts after co-culture with B16 cells.

Figure 7

(a) Schematic representation of in vitro macrophage cultivation and implantation with B16 tumor cells. (b) Representative images of B16 tumors 16 days post-inoculation; n = 5 for each group. (c) Tumor weights. (d) Tumor volumes; data were analyzed with one-way ANOVA. (e) Representative graphs of flow cytometry analysis of infiltrating M1 and M2 TAMs within tumors. (f, g, h, i) Infiltrating TAMs, CD8+ T cells, M1 and M2 TAM fractions and the M1: M2 ratio; n = 4 for each group. *P ≤ 0.05, **P ≤ 0.01, n.s., not significant.

HHS Vulnerability Disclosure