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Inhibition rates and aPTT results for best variants.
| Variants | k2 (M−1·s−1) | aPTT (s) NR = 49.3 ± 2.5 | ||
|---|---|---|---|---|
| APC | Thrombin | fXa | ||
| RRQ α1AT | (8.3 ± 1.1) × 103 | (5.4 ± 1.1) × 100 | (1.3 ± 0.1) × 102 | 55.1 ± 2.8 |
| KRQ α1AT | (9.0 ± 0.7) × 103 | (2.9 ± 1.5) × 100 | (1.7 ± 0.1) × 102 | 53.9 ± 3.0 |
NR is the value for the buffer only control.
