Table 2.
Correlation of original and calibrated SBRs and intraclass correlation coefficients (ICCs) between NOACNOSC (X-axis) and other reconstruction conditions (Y-axis) in healthy controls
| Reconstruction conditions | Number of SPECT scans | Average SBR | Range (min, max) | Linear regression equation | ICC (ρ) | 95% confidence interval of ICC (ρ) |
|---|---|---|---|---|---|---|
| Original | ||||||
| CTACSC | 292 | 9.12 | 4.41, 14.31 | Y = 1.200X + 2.334 | 0.438 | −0.096, 0.781 |
| ChangACSC | 510 | 10.48 | 5.41, 19.08 | Y = 1.445X + 2.138 | 0.333 | −0.075, 0.698 |
| CTACNOSC | 292 | 6.72 | 3.32, 11.46 | Y = 0.996X + 1.091 | 0.860 | −0.126, 0.963 |
| ChangACNOSC | 510 | 7.09 | 3.40, 12.21 | Y = 1.121X + 0.618 | 0.808 | −0.159, 0.945 |
| NOACNOSC | 510 | 5.77 | 2.18, 10.94 | NA | NA | NA |
| Calibrated | ||||||
| CTACSC | 292 | 8.96 | 4.37, 13.76 | Y = 1.053X + 0.517 | 0.832 | 0.372, 0.928 |
| ChangACSC | 510 | 9.31 | 4.10, 17.05 | Y = 1.103X + 0.297 | 0.820 | 0.222, 0.928 |
| CTACNOSC | 292 | 7.63 | 3.35, 11.83 | Y = 0.825X + 1.011 | 0.926 | 0.839, 0.959 |
| ChangACNOSC | 510 | 7.95 | 3.97, 14.66 | Y = 0.927X + 0.380 | 0.958 | 0.940, 0.969 |
| NOACNOSC | 510 | 8.16 | 3.81, 13.89 | NA | NA | NA |
CTACSC computed tomography attenuation correction with scatter correction, ChangACSC Chang attenuation correction with scatter correction, CTACNOSC computed tomography attenuation correction without scatter correction, ChangACNOSC Chang attenuation correction without scatter correction, NOACNOSC without attenuation or scatter correction