Table 1.
Parameters | Normal Control | Arsenic Trioxide | Eugenol | Arsenic Trioxide+Eugenol |
---|---|---|---|---|
GSH (µM/g tissue) | 52.04±0.72 | 23.72±1.24a | 40.92±0.81 | 42.38±0.18b |
GST(µM of CDNB- GSH conjugate formed/min/mg protein) | 2.54±0.56 | 1.49±0.99a | 2.18±0.06 | 2.72±0.03b |
GPx (µg of GSH consumed/min/mg protein) | 12.16±3.22 | 7.38±0.87a | 11.08±0.16 | 8.92±0.01b |
CAT (µmoles of H2O2 consumed/min/mg protein) | 39.66±0.14 | 16.07±0.51a | 38.00±0.18 | 33.40±0.11b |
GSH: Glutathione; GST: Glutathione S transferase; GPx: Glutathione peroxidase; CAT: Catalase; Table 1 depicts the effects of eugenol on the hepatic antioxidant system. Here the experimental group comprises normal control, arsenic trioxide (4 mg/ kg bwt), eugenol (5 mg/kg bwt), and arsenic trioxide (4 mg/ kg bwt)+eugenol (5 mg/ kg bwt). Data are presented as mean±SD and n=6. ‘a’ indicates a significant difference between the normal control group and the arsenic trioxide group. ‘b’ indicates a significant difference between the arsenic trioxide group and the arsenic trioxide+eugenol group.