Table 5.
Comparison of antibiogram (%R) of 167 viridans streptococci isolated from subgingival plaque and 58 viridans streptococci from blood of patients of periodontitis undergoing tooth extraction (n = 34).
| Viridans streptococci species | PEN | AMP | FEP | CTX | CRO | VAN | ERY | AZM | CLR | TCY | LVX | OFX | CLI | QDA | LNZ | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| %R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
% R |
||||||||||||||||
| Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | Pq | Bd | |
| S. mitis | 18 | 8 | 13 | 8 | 16 | 8 | 34 | 15 | 29 | 8 | 0 | 0 | 63 | 46 | 66 | 69 | 24 | 23 | 32 | 8 | 26 | 8 | 11 | 8 | 47 | 31 | 26 | 8 | 0 | 0 |
| S. oralis | 18 | 10 | 9 | 10 | 15 | 10 | 24 | 20 | 15 | 10 | 0 | 0 | 58 | 60 | 70 | 60 | 21 | 20 | 24 | 20 | 15 | 30 | 9 | 20 | 48 | 40 | 21 | 10 | 0 | 0 |
| S. sanguinis | 13 | 11 | 13 | 11 | 9 | 22 | 26 | 33 | 9 | 22 | 0 | 0 | 70 | 56 | 22 | 67 | 17 | 11 | 13 | 11 | 17 | 22 | 13 | 11 | 30 | 33 | 13 | 11 | 0 | 0 |
| S. parasanguinis | 0 | 0 | 0 | 0 | 14 | 50 | 14 | 0 | 0 | 0 | 0 | 0 | 14 | 0 | 29 | 100 | 14 | 0 | 14 | 0 | 14 | 0 | 14 | 0 | 14 | 50 | 0 | 50 | 0 | 0 |
| S. gordonii | 0 | 0 | 0 | 0 | 33 | 0 | 33 | 0 | 0 | 0 | 0 | 0 | 67 | 0 | 33 | 50 | 33 | 0 | 33 | 0 | 33 | 0 | 33 | 50 | 33 | 0 | 0 | 0 | 0 | 0 |
| S. anginosus | 0 | 0 | 0 | 0 | 0 | 0 | 25 | 0 | 0 | 0 | 0 | 0 | 25 | 0 | 25 | 100 | 25 | 0 | 0 | 0 | 50 | 0 | 25 | 0 | 25 | 0 | 0 | 0 | 0 | 0 |
| S. constellatus | 0 | 0 | 0 | 0 | 20 | 0 | 20 | 0 | 20 | 0 | 0 | 0 | 20 | 0 | 20 | 100 | 0 | 0 | 20 | 0 | 0 | 0 | 20 | 0 | 20 | 100 | 0 | 0 | 0 | 0 |
| S. mutans | 6 | 14 | 0 | 14 | 13 | 29 | 6 | 14 | 6 | 14 | 0 | 0 | 31 | 71 | 31 | 57 | 13 | 14 | 13 | 14 | 13 | 14 | 13 | 14 | 38 | 57 | 6 | 0 | 0 | 0 |
| S. hyointestinalis | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – |
| S. sinensis | 0 | 0 | 0 | 0 | 100 | 0 | 100 | 0 | 0 | 0 | 0 | 0 | 100 | 0 | 100 | 100 | 100 | 0 | 0 | 0 | 100 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| S. pluranimalium | 0 | – | 100 | – | 0 | – | 0 | – | 0 | – | 0 | – | 100 | – | 100 | – | 100 | – | 0 | – | 100 | – | 100 | – | 100 | – | 0 | – | 0 | – |
| S. thoraltensis | 0 | – | 100 | – | 100 | – | 100 | – | 100 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – |
| S. tigurinus | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – |
| G. adiacens | 5 | 0 | 0 | 0 | 5 | 0 | 5 | 25 | 5 | 25 | 0 | 0 | 14 | 50 | 14 | 25 | 14 | 0 | 14 | 25 | 14 | 25 | 10 | 0 | 24 | 25 | 0 | 25 | 0 | 0 |
| G. elegans | 8 | 13 | 0 | 13 | 17 | 13 | 25 | 13 | 8 | 13 | 0 | 0 | 42 | 50 | 50 | 38 | 17 | 25 | 17 | 25 | 17 | 13 | 8 | 13 | 42 | 25 | 25 | 13 | 0 | 0 |
VGS—viridans group streptococci, Pq—plaque, Bd—blood, AMP—ampicillin, AZM—azithromycin, CLI—clindamycin, CLR—clarithromycin, CRO—cefitriaxone, CTX—cefotaxime, ERY—erythromycin, FEP—cefepime, LNZ—linezolid, LVX—levofloxacin, OFX—ofloxacin, PEN—penicillin, QDA—quinupristin/dalfopristin, TCY—tetracycline, VAN—vancomycin.
There was no statistically significance difference (p > 0.05) between antimicrobial pattern of resistance of subgingival plaque and blood isolates of periodontitis patients undergoing tooth extraction except S. sanguinis to azithromycin (Fisher's exact test was used).