Table 1.
Associations between CDH6 Expression and Clinicopathological Characteristics
| Characteristics | n | CDH6 Expression |
p Values | |
|---|---|---|---|---|
| High (n, %) | Low (n, %) | |||
| Gender | ||||
| Male | 76 | 46 (60.5%) | 30 (39.5%) | 0.088 |
| Female | 57 | 26 (45.6%) | 31 (54.4%) | |
| Tumor Size (cm) | ||||
| >7 | 69 | 49 (71.0%) | 20 (29.0%) | 4.985 × 10−5** |
| ≤7 | 64 | 23 (35.9%) | 41 (64.1%) | |
| Location | ||||
| Distal femur | 57 | 32 (56.1%) | 25 (43.9%) | 0.366 |
| Proximal tibia | 34 | 19 (55.9%) | 15 (44.1%) | |
| Proximal humerus | 26 | 10 (38.5%) | 16 (61.5%) | |
| Proximal femur | 11 | 8 (72.7%) | 3 (27.3%) | |
| Others | 5 | 3 (60.0%) | 2 (40.0%) | |
| TNM Stage | ||||
| I | 57 | 16 (28.1%) | 41 (71.9%) | 1.747 × 10−7** |
| II/III | 76 | 56 (73.7%) | 20 (26.3%) | |
| Relapse | ||||
| Yes | 26 | 24 (92.3%) | 2 (7.7%) | 1.331 × 10−5** |
| No | 107 | 48 (44.9%) | 59 (55.1%) | |
| Metastasis | ||||
| Lung | 49 | 35 (71.4%) | 14 (28.6%) | 0.005** |
| Others | 16 | 9 (56.3%) | 7 (43.8%) | |
| No | 68 | 28 (41.2%) | 40 (58.8%) | |
p values were calculated by Pearson’s chi-square test. **p < 0.01. TNM, tumor, node, metastasis.