Table 2.
Associations between miR-223-3p Expression and Clinicopathological Characteristics
| Characteristics | n | miR-223-3p Expression |
p Values | |
|---|---|---|---|---|
| High (n, %) | Low (n, %) | |||
| Gender | ||||
| Male | 76 | 29 (38.2%) | 47 (61.8%) | 0.798 |
| Female | 57 | 23 (40.4%) | 34 (59.6%) | |
| Tumor Size (cm) | ||||
| >7 | 69 | 19 (27.5%) | 50 (72.5%) | 0.005** |
| ≤7 | 64 | 33 (51.6%) | 31 (48.4%) | |
| Location | ||||
| Distal femur | 57 | 24 (42.1%) | 33 (57.9%) | 0.241 |
| Proximal tibia | 34 | 16 (47.1%) | 18 (52.9%) | |
| Proximal humerus | 26 | 6 (23.1%) | 20 (76.9%) | |
| Proximal femur | 11 | 3 (27.3%) | 8 (72.7%) | |
| Others | 5 | 3 (60.0%) | 2 (40.0%) | |
| TNM Stage | ||||
| I | 57 | 38 (66.7%) | 19 (33.3%) | 1.674 × 10−8** |
| II/III | 76 | 14 (18.4%) | 62 (81.6%) | |
| Relapse | ||||
| Yes | 26 | 3 (11.5%) | 23 (88.5%) | 0.001** |
| No | 107 | 49 (45.8%) | 58 (54.2%) | |
| Metastasis | ||||
| Lung | 49 | 7 (14.3%) | 42 (85.7%) | 2.660 × 10−5** |
| Others | 16 | 8 (47.1%) | 9 (52.9%) | |
| No | 68 | 38 (55.9%) | 30 (44.1%) | |
p values were calculated by Pearson’s chi-square test. **p < 0.01. TNM, tumor, node, metastasis.