Table 3.

Univariate and multivariate analysis of disease-free survival

	Univariant analysis	p-value	Multivariant analysis	p-value
	HR (95% CI)		HR (95% CI)
Gender:male/female	0.77 (0.37–1.59)	NS
Child-Pugh score: A/B	0.94 (0.32–1.61)	NS
HBV DNA ≤ 4 (log copies/mL)	0.71 (0.33–1.54)	NS
HBeAg: negative/positive	0.61 (0.11–0.91)	< 0.05
Non-cirrhosis/Cirrhosis	0.47 (0.21–0.98)	< 0.05	0.41 (0.13–0.77)	< 0.05
Total bilirubin: <  24/≥ 24 (μmol/L)	1.15 (0.69–1.91)	NS
TDF treatment/ETV treatment	0.78 (0.43–0.97)	< 0.05	0.35 (0.33–0.84)	< 0.05

AFP = α-fetoprotein; HBeAg = hepatitis B e antigen; HBV = hepatitis B virus