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. 2018 Jun 8;14:179. doi: 10.1186/s12917-018-1509-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Immunoelectron microscopy images of exosomes isolated from samples of canine origin. a and b serum-derived exosomes, c C2 cell line culture-derived exosomes, d and e primary fibroblasts culture-derived exosomes. Note the gold particles bound to the exosome membrane indicating presence of the tetraspanin CD63. Size bar = 100 nm