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. 2018 Jun 8;18:36. doi: 10.1186/s12902-018-0267-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Overview of thyroid immune-related adverse events (irAEs) in patients with melanoma treated with nivolumab

The continuous levothyroxine replacement was needed in two out of three hypothyroid patients who had preceding transient thyrotoxicosis and in only one out of four hypothyroid patients without preceding thyrotoxicosis.

Abbreviations: irAE, immune-related adverse event