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. 2018 Jun 8;16:26. doi: 10.1186/s12964-018-0241-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — KL expression is negatively correlated with¹⁸F-FDG PET/CT SUVmax value. In order to assess the contribution of KL expression on metabolic burden, we evaluated the correlation between KL expression and SUVmax value obtained from PET/CT scanning by IHC staining. Representative images from PET/CT scanning in patients with low or high KL expression (magnification scale bar, 20 mm) (a). Analysis of the correlation between SUVmax value with KL expression in KL-Low and KL-High groups of patients (n = 71, p < 0.001) (b)