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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Breast Cancer Res Treat. 2018 Feb 22;170(1):101–109. doi: 10.1007/s10549-018-4727-9

Table 7.

Baseline characteristics between adjuvant and neoadjuvant treatments for matched patients (85 matched pairs and n = 170 patients)

Variable Overall (%) Adjuvant (n = 85) Neodjuvant (n = 85) Standard
mean difference
Age
  < 50 129 (75.9) 64 (75.3) 65 (76.5) 0.028
  > 50 41 (24.1) 21 (24.7) 20 (23.5)
Race
  Black 26 (15.3) 15 (17.6) 11 (12.9)
  Hispanic 29 (17.1) 13 (15.3) 16 (18.8) 0.099
  Other 12 (7.1) 6 (7.1) 6 (7.1) 0.000
  White 103 (60.6) 51 (60.0) 52 (61.2) 0.024
Prevalence of other cancers
  No 153 (90.0) 75 (88.2) 78 (91.8) − 0.154
  Yes 17 (10.0) 10 (11.8) 7 (8.2)
Premenopausal at diagnosis
  No 49 (28.8) 24 (28.2) 25 (29.4) − 0.027
  Yes 121 (71.2) 61 (71.8) 60 (70.6)
Second primary breast cancer
  No 158 (92.9) 79 (92.9) 79 (92.9) 0.000
  Yes 12 (7.1) 6 (7.1) 6 (7.1)
T stage
  T1 53 (31.2) 29 (34.1) 24 (28.2) 0.150
  T2 117 (68.8) 56 (65.9) 61 (71.8)
N stage
  N0 107 (62.9) 58 (68.2) 49 (57.6) 0.215
  N1 63 (37.1) 27 (31.8) 36 (42.4)
Clinical stage
  Stage IA 35 (20.6) 20 (23.5) 15 (17.6)
  Stage IIA 90 (52.9) 47 (55.3) 43 (50.6) − 0.094
  Stage IIB 45 (26.5) 18 (21.2) 27 (31.8) 0.223
Histology
  IDC 167 (98.2) 83 (97.6) 84 (98.8)
  IDC-ILC 0 (0) 0 (0) 0 (0)
  Other 3 (1.8) 2 (2.4) 1 (1.2) − 0.094
Nuclear grade
  Grade 1 2 (1.2) 2 (2.4) 0 (0)
  Grade 2 5 (3.0) 1 (1.2) 4 (4.7) − 0.164
  Grade 3 160 (95.8) 79 (96.3) 81 (95.3) 0.049
Type of surgical therapy
  Partial mastectomy 77 (45.3) 41 (48.2) 36 (42.4) 0.121
  Total mastectomy 93 (54.7) 44 (51.8) 49 (57.6)
BRCA status
  Negative 102 (60.0) 51 (60.0) 51 (60.0) 0.000
  Positive 68 (40.0) 34 (40.0) 34 (40.0)
Chemotherapy agent
  Anthracycline 24 (14.1) 15 (17.6) 9 (10.6)
  Anthracycline + Taxane 140 (82.4) 67 (78.8) 73 (85.9) 0.240
  Other 6 (3.5) 3 (3.5) 3 (3.5) 0.000
Total chemotherapy completed
  < 75% 5 (2.9) 3 (3.5) 2 (2.4) 0.094
  > 75% 165 (97.1) 82 (96.5) 83 (97.6)
Radiation
  No 73 (42.9) 40 (47.1) 33 (38.8) 0.169
  Yes 97 (57.1) 45 (52.9) 52 (61.2)