Table 7.
Variable | Overall (%) | Adjuvant (n = 85) | Neodjuvant (n = 85) | Standard mean difference |
---|---|---|---|---|
Age | ||||
< 50 | 129 (75.9) | 64 (75.3) | 65 (76.5) | 0.028 |
> 50 | 41 (24.1) | 21 (24.7) | 20 (23.5) | |
Race | ||||
Black | 26 (15.3) | 15 (17.6) | 11 (12.9) | |
Hispanic | 29 (17.1) | 13 (15.3) | 16 (18.8) | 0.099 |
Other | 12 (7.1) | 6 (7.1) | 6 (7.1) | 0.000 |
White | 103 (60.6) | 51 (60.0) | 52 (61.2) | 0.024 |
Prevalence of other cancers | ||||
No | 153 (90.0) | 75 (88.2) | 78 (91.8) | − 0.154 |
Yes | 17 (10.0) | 10 (11.8) | 7 (8.2) | |
Premenopausal at diagnosis | ||||
No | 49 (28.8) | 24 (28.2) | 25 (29.4) | − 0.027 |
Yes | 121 (71.2) | 61 (71.8) | 60 (70.6) | |
Second primary breast cancer | ||||
No | 158 (92.9) | 79 (92.9) | 79 (92.9) | 0.000 |
Yes | 12 (7.1) | 6 (7.1) | 6 (7.1) | |
T stage | ||||
T1 | 53 (31.2) | 29 (34.1) | 24 (28.2) | 0.150 |
T2 | 117 (68.8) | 56 (65.9) | 61 (71.8) | |
N stage | ||||
N0 | 107 (62.9) | 58 (68.2) | 49 (57.6) | 0.215 |
N1 | 63 (37.1) | 27 (31.8) | 36 (42.4) | |
Clinical stage | ||||
Stage IA | 35 (20.6) | 20 (23.5) | 15 (17.6) | |
Stage IIA | 90 (52.9) | 47 (55.3) | 43 (50.6) | − 0.094 |
Stage IIB | 45 (26.5) | 18 (21.2) | 27 (31.8) | 0.223 |
Histology | ||||
IDC | 167 (98.2) | 83 (97.6) | 84 (98.8) | |
IDC-ILC | 0 (0) | 0 (0) | 0 (0) | |
Other | 3 (1.8) | 2 (2.4) | 1 (1.2) | − 0.094 |
Nuclear grade | ||||
Grade 1 | 2 (1.2) | 2 (2.4) | 0 (0) | |
Grade 2 | 5 (3.0) | 1 (1.2) | 4 (4.7) | − 0.164 |
Grade 3 | 160 (95.8) | 79 (96.3) | 81 (95.3) | 0.049 |
Type of surgical therapy | ||||
Partial mastectomy | 77 (45.3) | 41 (48.2) | 36 (42.4) | 0.121 |
Total mastectomy | 93 (54.7) | 44 (51.8) | 49 (57.6) | |
BRCA status | ||||
Negative | 102 (60.0) | 51 (60.0) | 51 (60.0) | 0.000 |
Positive | 68 (40.0) | 34 (40.0) | 34 (40.0) | |
Chemotherapy agent | ||||
Anthracycline | 24 (14.1) | 15 (17.6) | 9 (10.6) | |
Anthracycline + Taxane | 140 (82.4) | 67 (78.8) | 73 (85.9) | 0.240 |
Other | 6 (3.5) | 3 (3.5) | 3 (3.5) | 0.000 |
Total chemotherapy completed | ||||
< 75% | 5 (2.9) | 3 (3.5) | 2 (2.4) | 0.094 |
> 75% | 165 (97.1) | 82 (96.5) | 83 (97.6) | |
Radiation | ||||
No | 73 (42.9) | 40 (47.1) | 33 (38.8) | 0.169 |
Yes | 97 (57.1) | 45 (52.9) | 52 (61.2) |