Table 5.
Axon integrity with glaucoma exposure
| Group | # Nerves | # Axons | # Fragments per Axon | Median Fragment Length | Mean Total Fragment Length | Mean Axon Length |
|---|---|---|---|---|---|---|
| Young, Control | 3 | 23 | 1.0 | 353 | 388 ± 38 | 393 ± 38 |
| Young, 14 hr GL | 6 | 77 | 8.0 | 35 | 318 ± 108 | 395 ± 55 |
| Young, 1 day GL | 5 | 29 | 6.0 | 34 | 341 ± 147 | 375 ± 81 |
| Young, 4 day GL | 7 | 34 | 6.5 | 21 | 215 ± 139 | 379 ± 91 |
| Old, Control | 18 | 294 | 3.0 | 420 | 368 ± 92 | 383 ± 78 |
| Old, 14 hr GL | 5 | 76 | 9.5 | 40 | 345 ± 109 | 395 ± 64 |
| Old, 1 day GL | 5 | 46 | 9.0 | 26 | 268 ± 115 | 307 ±113 |
| Old, 4 day GL | 3 | 44 | 11.0 | 25 | 288 ± 97 | 393 ± 50 |
GL = glaucoma group; hr = hour
*
The data for younger RGC-YFP mice is from explants whose data were reported previously (Kimball et al., 2017).