Table 1.
Lean Young | MetS Young | Lean Old | MetS Old | |
---|---|---|---|---|
Age (years) | 2.0 ± 0.0 | 2.5 ± 0.2 | 9.2 ± 1.1* † | 8.8 ± 1.2* † |
Body Weight (kg) | 74 ± 4 | 108 ± 2* | 87 ± 5† | 113 ± 7* ‡ |
Sex (Male/Female) | 2/4 | 0/10 | 3/2 | 0/3 |
Total Cholesterol (mg/dL) | 77 ± 6 | 474 ± 79* | 60 ± 4† | 411 ± 66‡ |
Triglycerides (mg/dL) | 65 ± 18 | 56 ± 5 | 17 ± 4* † | 20 ± 6 |
Fasting Glucose (mg/dL) | 70 ± 2 | 81 ± 2 | 52 ± 12† | 78 ± 7 |
Peak Glucose (mg/dL) | 563 ± 27 | 755 ± 22* | 688 ± 20 | 733 ± 44* |
Blood Glucose AUC | 10120 ± 667 | 18124 ± 919* | 12237 ± 464† | 15297 ± 1556* |
Data are means ± SEM. MetS, metabolic syndrome; MAP, mean arterial pressure; AUC, area under curve. Fasting glucose was taken during intravenous glucose tolerance tests or during routine blood glucose monitoring for the lean old group.
p < 0.05 compared with young lean swine;
p < 0.05 compared with young MetS swine;
p < 0.05 compared with old lean swine.