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Lipidomic analysis of lipid raft fractions. a, b Quantitation of 34:1 sphingomyelin and its corresponding ceramide species. There is no significant difference between vehicle- and GW4869 nSMase inhibitor-treated groups. c–f Quantitation of longer chain 36:1 and 38:1 sphingomyelins and their corresponding ceramides. Sphingomyelins, but not ceramides, were significantly reduced by inhibitor treatment. Asterisks indicate significant differences compared to controls *p < 0.05
