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. 2017 Oct 17;55(7):5741–5756. doi: 10.1007/s12035-017-0784-z

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 7 — a Rotarod performance (saline vs GW4869 nSMase inhibitor). Histograms represent the time spent by rats injected with saline and rats injected with GW4869 walking on the accelerating rotating rod. Animals were tested 6-h post intrastriatal injection. Data represents the mean and standard error from n = 6 Wistar rats in each group. Each bar in the diagram indicates mean + SEM. b Beam crossing test (saline vs inhibitor). Histograms represent the time spent by rats injected with saline and rats injected with GW4860 to cross the beam. Rats that fell off the beam or were unable to cross the beam successfully after 60 s were given a maximum score of 60 s. Animals were tested 6-h post intrastriatal injection. Data represents the mean and standard error from n = 6 Wistar rats in each group. Each bar in the diagram indicates mean + SEM. Asterisks indicate significant differences compared to controls: *p < 0.05, **p < 0.01, ***p < 0.001