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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Alzheimers Dement. 2018 Jan 4;14(6):797–810. doi: 10.1016/j.jalz.2017.11.014

Figure 2.

Figure 2

Glass Brain representation of NDM predicted atrophy over time (t). The blue spheres depict the affected regions and indicate a propagation of AD pathology that can be partially recapitulated by a single regional seed at the entorhinal cortex of the NDM. Regional seeding with the NDM propagates into atrophy patterns that have a high correspondence to cross-sectional atrophy of AD patients. Seeding for all regions were conducted; however, the figure represents seeding at the Entorhinal Cortex which resulted in a high correlation strength (Rmax = 0.56, p = 2.03 E-08).