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. 2018 Jun 4;9:1158. doi: 10.3389/fimmu.2018.01158

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Copyright © 2018 Cueno and Ochiai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Network analyses of representative biochemical components affected by gingival periodontal disease level-butyric acid. (A) Network design of both the blood and brain biochemical components. Edge betweenness centrality data analyses are indicated over the arrows. Edge betweenness threshold is shown. (B) Centrality analyses of the blood and brain biochemical components. Values for stress, betweenness closeness, eccentricity, and radiality centralities of each component are indicated. Node threshold for each centrality measurement is shown.