Table 2.
Oxygen saturation, acute mountain sickness and trail making tests during acute and acclimatization exposures.
| Variables |
Cycle 1 |
Cycle 2 |
||||||
|---|---|---|---|---|---|---|---|---|
| Baseline SL | HA1 | HA6 | Recover SL | Baseline SL | HA1 | HA6 | Recover SL | |
| SpO2 (%) | 98.0 ± 0.9 | 80.2 ± 4.7* | 83.7 ± 4.5*† | 98.0 ± 1.2 | 98.4 ± 1.1 | 82.8 ± 6.6* | 85.0 ± 4.0* | 97.8 ± 1.3 |
| Lake Louise Score (LLS) | 0.8 ± 1.4 | 5.4 ± 3.1* | 1.9 ± 2.0† | 0.5 ± 0.8 | 1.7 ± 1.8 | 4.2 ± 2.7* | 2.0 ± 2.1† | 0.9 ± 1.2 |
| AMS, n (%) | – | 12 (57) | 2 (10) | – | 1 (5) | 6 (29) | 2 (10) | – |
| AMS-C (ESQ) | 0.1 ± 0.2 | 1.0 ± 0.8* | 0.2 ± 0.2† | 0 ± 0.1 | 0.1 ± 0.2 | 0.6 ± 0.6* | 0.2 ± 0.3† | 0 ± 0 |
| AMS, n (%) | – | 13 (62) | 0 (0) | – | 1 (5) | 6 (29) | 2 (10) | – |
| Trail making test (TMT) | ||||||||
| Time (s) | 49.0 ± 11.5 | 48.1 ± 13.3 | 42.4 ± 9.7*† | 41.3 ± 8.8 | 41.5 ± 9.4 | 41.3 ± 9.6 | 37.7 ± 8.2*† | 37.1 ± 7.9 |
Values are means ± SD. SL, sea level; HA1, high altitude at day 1; HA6, high altitude day 6; n, numbers; SpO2, blood oxygen saturation; LLS, Lake Louise Score; AMS, acute mountain sickness; AMS-C, acute mountain sickness – cerebral; ESQ, Environmental Symptom Questionnaire. an = 20; ∗p < 0.05: Different from respective baseline SL; †p < 0.05: Different from respective HA1.