Figure 8.
rfhSP-D downregulated the survival pathway, mTOR. (A) rfhSP-D treatment of Panc-1 and MiaPaCa-2 cells downregulated the mRNA expression of mTOR (****p < 0.0001). (B) Immunofluorescence microscopy showed reduced cytoplasmic levels of mTOR following treatment as compared to the untreated. Nuclear accumulation is clearly visible in the rfhSP-D treated cells.