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. 2018 Jun 4;9:657. doi: 10.3389/fphys.2018.00657

Figure 1.

Figure 1

ADM scaffolds induce recruitment of macrophages in skin-wound healing. (A) Word map showing key objectives of the study. (B) TPF/SHG 3D scanning images of N-ADM and A-ADM scaffolds (up); 2D images of N-ADM and A-ADM scaffolds (down). (C) Ultrastructural images of collagen fibrils in N-ADM and A-ADM scaffolds. (D) Representative H&E staining of wounds at 10 days after injury. (E) Quantification of the hemorrhage area in wound tissue (n = 5 from two experiments). (F) Representative micrographs showing immunostaining of macrophages with F4/80 at 10 days after injury. (G) Quantification of F4/80-positive cells in wound tissue (n = 5 mice from two experiments). ANOVA: *P < 0.05, **P < 0.01, ***P < 0.001.