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. 2018 Jun 4;9:1197. doi: 10.3389/fimmu.2018.01197

Figure 3.

Figure 3

Localization of enhanced expression of NLRP1, NLRP3, NLRC4, and absent in melanoma 2 (AIM2) in thyroid cells in areas of lymphatic infiltration. (A) Representative immunohistochemical staining images of AIM2, NLRP3, NLRP1, and NLRC4 in thyroid tissue sections from AIT patients and controls (400× magnification, light microscope). (B) Quantified expression levels of AIM2, NLRP3, NLRP1, and NLRC4 in control and AIT tissues (N = 20 in each group). The columns represent the mean ± SD values. Three views were randomly selected in each subject. Statistical analysis was carried out using Student’s t-test. *P < 0.05, **P < 0.01. AIT, autoimmune thyroiditis; CON, controls; IIA, inflammatory infiltration area; NIIA, non-inflammatory infiltration area.