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. 2018 May;10(Suppl 13):S1482–S1493. doi: 10.21037/jtd.2018.05.106

Table 1. Long-term survival in NSCLC with PD-1/PD-L1 inhibitors.

Drugs Clinical trials 2-year OS (%) 3-year OS (%) 5-year OS (%)
Pembrolizumab Keynote 001 (treated native pts vs. previously treated pts) 44.5 vs. 31.3 26.4 vs. 19.0 Keynote 010 21.5
Nivolumab CM017 (SQ) (Nivo vs. docetaxel) 23.0 vs. 8.0 16.0 vs. 6.0 CA209-003 SQ vs. non-SQ: 16.0 vs. 15.0
CM057 (non-SQ) (Nivo vs. docetaxel) 29.0 vs. 16.0 18.0 vs. 9.0
Atezolizumab OAK (Atezo vs. docetaxel) 31.0 vs. 21.0

NSCLC, non-small cell lung cancer; Pts, patients; CM, checkmate; SQ, squamous lung cancer; non-SQ, non-squamous lung cancer; Nivo, nivolumab; Atezo, atezolizumab; OS, overall survival.