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. 2018 May;10(Suppl 13):S1509–S1515. doi: 10.21037/jtd.2017.10.157

Table 2. Clinicopathological features and prognostic significance associated with PD-L1 expression in thymic epithelial tumors.

Studies Factors associated with high PD-L1 expression Prognostic impact of high PD-L1 expression
Padda et al. (13) Younger age, high stage, incomplete resection, aggressive histology Worse OS (age- and sex-adjusted analysis)
Katsuya et al. (14) Thymic carcinoma (rather than thymoma) None
Yokoyama et al. (15) Masaoka stage III/IV, WHO type B2/B3 Worse DFS
Yokoyama et al. (16) None Better OS
Marchevsky et al. (17) Aggressive histology
Weissferdt et al. (18) Neoadjuvant therapy in thymoma None
Arbour et al. (19) Thymoma (rather than thymic carcinoma) Better OS

PD-L1, programmed death ligand 1; WHO, World Health Organization; OS, overall survival; DFS, disease-free survival.