Table 1. Rare coding variants of UNC5C related to LOAD.
| UNC5C SNPs | Risk allele | AA variation | Exon location | P | Population |
|---|---|---|---|---|---|
| rs137875858 | A | T835M | Exon 15 | 0.0095 | European population |
| rs145155041 | T | D353N | Exon 7 | N/A | European population |
| rs372767649 | G | Q860H | Exon 15 | 0.017 | Han Chinese |
| rs368284839 | A | T837K | Exon 15 | 0.13 | Han Chinese |
| rs779272234 | G | S843G | Exon 15 | 0.36 | Han Chinese |
| rs745871673 | G | V836V | Exon 15 | 0.36 | Han Chinese |
P value was determined using Fisher exact test. LOAD, late-onset Alzheimer’s disease; SNP, single-nucleotide polymorphism; N/A, not applicable.