Table 1. Summary of drug effects on the locomotor activity, including the activity and the possible target.
| Compound name | Activities | Influence under light* | Influence under dark** | Target |
|---|---|---|---|---|
| Sulpiride | Dopamine receptor antagonist | No difference | No difference | Excitatory neuron |
| 5,5-Diphenylhydantoin | Sodium channel antagonist | No difference | Downward trend | Excitatory neuron |
| MK-801 | NMDA receptor antagonist | Downward trend | Downward trend | Excitatory neuron |
| Valproic acid | Histone acetylation enzyme inhibitor | Downward trend | Downward trend | – |
| Yohimbine | α2-adrenaline receptor antagonist | Downward trend | Downward trend | – |
| Pentylenetetrazole | γ-aminobutyric acid receptor antagonist | Upward trend | Upward trend | Inhibitory neuron |
*, The influence of locomotion under the light condition; **, the influence of locomotion under the dark condition; –, there is no clear definition of the types of neurons.