3.

Non-invasive diagnostic model for liver fibrosis

Model	Formula
ALB: albumin; AST: aspartate aminotransferase; ALT: alanine transaminase; INR, international normalized ratio; GGT: gamma-glutamyl transferase; PLT: platelet; ULN: upper limit of normal; FibroQ: fibrosis quotient.
AAR26,27	AST(IU/L) / AST(IU/L)
APRI28	AST(IU/L) / PLT(109/l)
GPRI	GGT(IU/L) / PLT(109/l)
S index	1,000 × GGT (IU/L) / [PLT(109/l) × ALB2(g/L)]
APRI29	AST(IU/L) / ULN(IU/L) / PLT(109/l)
FIB-4 score	[Age (years) × AST(IU/L)] / PLT (109/l) × ALT1/2 (IU/L)
Fibro-Q	[10× AST(IU/L) × age (years) × INR] / PLT (109/l) × ALT (IU/L)
API (Age plus PLT)	Age (years): >70=5, 61–70=4, 51–60=3, 41–50=2, 31–40=1, ≤30=0 PLT (10 9/l): <125=5, 125–149=4, 150–174=3, 175–199=2, 200–224=1, ≥225=0
VITRO	von Willebrand factor antigen (vWF-Ag)/thrombocyte ratio
APRG30	ALP/PLT/RDW-SD/globulin