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. 2018 Jun 4;9:1226. doi: 10.3389/fimmu.2018.01226

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Copyright © 2018 Deng, Fan, Gao, Zeng, Guo, Wei, Chen, Chen, Gong, Feng, Xia, Xiang, Gong, Yuan, Shen, Shen, Lin, Jiang, He, Lu, Chen and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Signal transducer and activator of transcription 3 (STAT3) hyperactivation correlates with aberrant follicular helper T (Tfh) differentiation in patients with rheumatoid arthritis (RA). Statistics showing the relationship between the frequencies of indicated CD4⁺ T cell subsets with the phosphorylated STAT3 (pSTAT3) expression in total CD4⁺ T cells (A) or in each individual subsets (B) in the peripheral blood mononuclear cells from patients with RA. The correlation was determined using Spearman’s correlation coefficient.