Table 1.
Glycopyrrolate strength | Nebulization time (minutes) | MMAD (μm) | GSD | FPD (μg) | FPF (%) | NGI recovery (% nominal dose) |
---|---|---|---|---|---|---|
25 μg/mL | 1.88 ± 0.23 | 3.71 ± 0.26 | 1.66 ± 0.06 | 15.20 ± 1.26 | 72.28 ± 5.57 | 95.61 ± 1.90 |
50 μg/mL | 1.92 ± 0.14 | 3.74 ± 0.20 | 1.65 ± 0.04 | 30.44 ± 1.51 | 71.65 ± 4.34 | 94.94 ± 1.75 |
CS, Closed System; FPD, fine particle dose; FPF, fine particle fraction; GSD, geometric standard deviation; MMAD, mass median aerodynamic diameter; NGI, Next Generation Impactor.