Table 2.
Delivered Dose by Continuous Flow and by Breathing Simulation of Glycopyrrolate
| Results (n = 30, mean ± SD) | |||||
|---|---|---|---|---|---|
| Glycopyrrolate strength | Nebulization time (minutes) | Delivered dose (μg) | Delivered dose (% nominal dose) | Residual dose (% nominal dose) | Total recovery (% nominal dose) |
| Delivered dose by continuous flow method | |||||
| 25 μg/mL | 1.90 ± 0.29 | 21.93 ± 1.16 | 87.72 ± 4.65 | 13.19 ± 4.23 | 100.94 ± 2.70 |
| 50 μg/mL | 1.99 ± 0.21 | 44.11 ± 1.43 | 88.23 ± 2.86 | 9.21 ± 3.02 | 99.55 ± 1.92 |
| Delivered dose by breathing simulation method | |||||
| 25 μg/mL | 2.02 ± 0.31 | 14.20 ± 1.21 | 56.80 ± 4.83 | 25.55 ± 5.85 | 85.36 ± 2.13 |
| 50 μg/mL | 2.06 ± 0.24 | 31.29 ± 1.87 | 62.57 ± 3.74 | 25.56 ± 4.22 | 88.14 ± 1.56 |
SD, standard deviation.