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. 2018 Jun 1;28(3):166–177. doi: 10.1089/nat.2018.0727

FIG. 1.

FIG. 1.

Overview of the Endocytosis and Intracellular Trafficking of Oligonucleotides. Key elements of trafficking are depicted as described in the main text. The diagram does not show proposed sites of oligonucleotide release. EE, early endosome; MVB, multivesicular body; LE, late endosome, LY, lysosome; TGN, trans-Golgi network.