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. 2018 Jun 7;5(4):e466. doi: 10.1212/NXI.0000000000000466

Figure 3. Immunohistochemical analyses of positive and negative Epstein-Barr virus (EBV) control tissues using immunostaining.

Figure 3

Pictures are representative of results from 2 different experiments using EBV-positive (tonsil with infectious mononucleosis) and EBV-negative (normal tonsil) control samples. Immunohistochemistry revealed the presence of CD20+ B lymphocytes (A–B) and CD138+ plasma cells (C–D) in our positive and negative control tissue (A–D). LMP-1+ (brown staining) and BZLF1+ (brown staining emphasized with black arrows) cells are shown in a tonsil from a patient with infectious mononucleosis (E, G). No LMP-1+ or BZLF1+ cells were observed in our negative control tissue (normal tonsil) (F, H). Scale bar = 50 μm.