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Sirolimus data by azole.
| Variable | Fluconazole | Posaconazole | Voriconazole | All azoles |
|---|---|---|---|---|
| Highest recorded trough (ng/mL), mean ± SD | 17.2 ± 5.4 | 14.4 ± 5.3 | 10.2 ± 4.2 | – |
| Trough on discharge (ng/mL), mean ± SD | 7.8 ± 2.8 | 5.7 ± 2.8 | 7.3 ± 5.4 | – |
| Trough on discharge, median (range) | 7.1 (4.1–14.3) | 5.1 (3.1–9.6) | 8.7 (2.8–13.5) | – |
| Therapeutic (goal 3–12 ng/mL), yes (%) | 20 (95.2) | 4 (100) | 1 (33.3) | 25 (89.3) |
| Maintenance oral dose at discharge (mg/day), mean ± SD | 1.7 ± 1.1 | 1.3 ± 0.5 | 1.2 ± 0.8 | – |
