Effects of IL-2C on non-Treg cell populations at day 5 post-Tx (4 mice/group). A, Increased percentage of CD8 T cells in allograft recipients treated with IL-2C post-Tx. B, Increased proliferation of CD4+ T cells in allograft recipients treated with IL-2C post-Tx. C, Increased proliferation of CD8+ Tcells in allograft recipients treated with IL-2C post-Tx. D, Increased production of IFN-γ by CD4+ Tcells in allograft recipients. E, Increased production of IFN-γ by CD8+ Tcells in allograft recipients. F, Ratio of Ki67+ Treg cells to CD4 + Foxp3- or CD8 + Foxp3- Tcells; higher ratios were associated with longer allograft survival.